Danielsen T E, Langård S, Andersen A, Knudsen O
Telemark Central Hospital, Department of Occupational Medicine, Porsgrunn, Norway.
Br J Ind Med. 1993 Dec;50(12):1097-103. doi: 10.1136/oem.50.12.1097.
The incidence of cancer among 4571 shipyard workers with first employment between 1940 and 1979, including 623 welders of mild steel, was investigated in a historical cohort study. The loss to follow up was 1.1%. The total number of deaths was 1078 (974.5 expected) and there were 408 cases of cancer v 361.3 expected. Sixty five cases of lung cancer were found v 46.3 expected based on the national rates for males. Four pleural mesotheliomas had occurred (1.2 expected), none among the welders. An excess of lung cancers was found among the welders (nine cases v 3.6 expected). There were six cases of lung cancer v 1.6 expected in a high exposure group of 255 welders. A survey of the smoking habits as of 1984 indicated 10%-20% more daily smokers among the shipyard production workers than among Norwegian males. Exposure to smoking and asbestos were confounding variables in this study.
在一项历史性队列研究中，对1940年至1979年间首次就业的4571名造船厂工人（包括623名低碳钢焊工）的癌症发病率进行了调查。随访失访率为1.1%。死亡总数为1078人（预期974.5人），癌症病例有408例，预期为361.3例。根据全国男性发病率，发现65例肺癌，预期为46.3例。发生了4例胸膜间皮瘤（预期1.2例），焊工中无一例。在焊工中发现肺癌病例过多（9例，预期3.6例）。在255名高暴露组焊工中，有6例肺癌，预期为1.6例。1984年对吸烟习惯的一项调查表明，造船厂生产工人中每日吸烟者比挪威男性多10%-20%。吸烟和石棉暴露是本研究中的混杂变量。
