Ray S
School of Biological and Molecular Sciences, Oxford Brookes University, UK.
Neurosci Lett. 1999 Jan 4;259(1):37-40. doi: 10.1016/s0304-3940(98)00892-1.
Metamorphosis in the fly (Musca domestica) involves extensive lysis, neurogenesis and reorganization of neural tissue. Despite this, two experiments are reported which show aspects of larval memory persist into the adult form. Experimental larvae were reared in sawdust scented with aversive odours (mint or geraniol). Control larvae were reared on plain sawdust. In blind post-metamorphosis testing using a Y maze, adult flies showed a preference for the specific odour to which the larvae had been exposed. Control flies found both test odours aversive. A second experiment explores the possible role of cell survival through metamorphosis as a mechanism of the persistence of memory. Cells from trained donor flies when grafted into untrained recipients produced specific changes in recipient odour preference reflecting the donor larvae training.
苍蝇（家蝇）的变态过程涉及神经组织的广泛溶解、神经发生和重组。尽管如此，仍有两项实验表明，幼虫记忆的某些方面会持续到成虫阶段。将实验幼虫饲养在带有厌恶气味（薄荷或香叶醇）的锯末中。对照幼虫饲养在普通锯末上。在变态后使用Y迷宫进行的盲测中，成年苍蝇表现出对幼虫接触过的特定气味的偏好。对照苍蝇觉得两种测试气味都很厌恶。第二项实验探讨了细胞在变态过程中存活作为记忆持续存在机制的可能作用。将经过训练的供体苍蝇的细胞移植到未经训练的受体中时，受体的气味偏好会产生特定变化，反映出供体幼虫的训练情况。
