Young A C, Saunders J, Ponsford J R
J Neurol Neurosurg Psychiatry. 1976 Oct;39(10):1008-13. doi: 10.1136/jnnp.39.10.1008.
Five patients with mental change as a prominent and early feature of an illness which appeared to be multiple sclerosis are reported. All the patients had in addition clinical signs of predominant brain stem involvement and the cerebrospinal fluid findings were similar. It is emphasised that mental change may be an early feature of multiple sclerosis even in those patients in whom the onset of the disease is insidious.
报告了5例以精神改变为突出且早期特征的疾病患者,该疾病似乎为多发性硬化症。所有患者还伴有以脑干受累为主的临床体征,且脑脊液检查结果相似。需要强调的是,即使在疾病起病隐匿的患者中,精神改变也可能是多发性硬化症的早期特征。