Motykie G D, Caprini J A, Arcelus J I, Reyna J J, Overom E, Mokhtee D
Department of Surgery, Evanston Northwestern Healthcare, Illinois 60201, USA.
Dermatol Surg. 1999 Feb;25(2):116-20. doi: 10.1046/j.1524-4725.1999.08095.x.
Chronic venous insufficiency (CVI) affects a significant portion of the world's population, causing substantial morbidity and medical expenditure. Its pathophysiology is based on venous hypertension in the lower extremities, with vascular compression therapy remaining the foundation of its medical management.
To evaluate the effectiveness of therapeutic compression stockings in the treatment of lower extremity CVI.
A group of 112 patients with CVI received graduated-compression stockings and rated the severity of their symptoms on a five-point scale before wearing the stockings, and then again after 1 and 16 months of treatment. Patient complaints associated with stocking use and patient compliance rates were also recorded at 1 and 16 months.
A statistically significant improvement (p < 0.001) was reported in patient severity scores for lower extremity swelling, pain, skin discoloration, activity tolerance, depression and sleeping problems after 1 and 16 months of treatment with compression stockings.
Therapeutic graduated-compression stockings are an effective treatment for CVI of the lower extremities.
慢性静脉功能不全（CVI）影响着世界上相当一部分人口，导致大量发病和医疗支出。其病理生理学基于下肢静脉高压，血管压迫疗法仍然是其药物治疗的基础。
评估治疗性压力袜治疗下肢CVI的有效性。
一组112例CVI患者接受了分级压力袜治疗，并在穿压力袜前、治疗1个月和16个月后采用五点量表对其症状严重程度进行评分。在1个月和16个月时还记录了与使用压力袜相关的患者主诉和患者依从率。
压力袜治疗1个月和16个月后，患者下肢肿胀、疼痛、皮肤变色、活动耐量、抑郁和睡眠问题的严重程度评分有统计学意义的改善（p < 0.001）。
治疗性分级压力袜是治疗下肢CVI的有效方法。
