Le K V, Shahidullah H, Frieden I J
Department of Dermatology, University of California, San Francisco, USA.
Dermatol Surg. 1999 Feb;25(2):127-32. doi: 10.1046/j.1524-4725.1999.08166.x.
Traditional mechanisms of assessing port-wine stain response to laser therapy have rested mainly on subjective determinations by physician and patient. However, the wide variation in treatment response poses a profound need for objective devices to measure treatment outcomes so that maximum effectiveness of therapy can be achieved without unnecessary repeat treatments.
The purpose of this paper will be to review noninvasive techniques to measure port-wine stain response to laser therapy.
This report is based on a review of medical and bioscience literature.
Several techniques including laser Doppler, reflectance spectrophotometry, tristimulus colorimetry, and videomicroscopy have been developed to address the need for objective measurement devices.
While many instruments are available, these techniques are limited by cost, small test size area, and/or inconclusive correlation with clinical response. A number of experimental techniques may circumvent many of the problems inherent in currently-available commercial technologies.
评估葡萄酒色斑对激光治疗反应的传统机制主要基于医生和患者的主观判断。然而，治疗反应的广泛差异迫切需要客观的设备来测量治疗结果，以便在无需不必要的重复治疗的情况下实现治疗的最大效果。
本文旨在综述测量葡萄酒色斑对激光治疗反应的非侵入性技术。
本报告基于对医学和生物科学文献的综述。
为满足对客观测量设备的需求，已开发出多种技术，包括激光多普勒、反射分光光度法、三刺激比色法和视频显微镜检查。
虽然有许多仪器可用，但这些技术受到成本、测试面积小和/或与临床反应的相关性不明确的限制。一些实验技术可能会规避当前可用商业技术中固有的许多问题。
