干扰素、双链RNA与mRNA降解 - Suppr

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Interferon, double-stranded RNA and mRNA degradation.

作者信息

Sen G C, Lebleu B, Brown G E, Kawakita M, Slattery E, Lengyel P

出版信息

Nature. 1976 Nov 25;264(5584):370-3. doi: 10.1038/264370a0.

DOI:10.1038/264370a0

PMID:1004563

Abstract

摘要

相似文献

Interferon, double-stranded RNA and mRNA degradation.干扰素、双链RNA与mRNA降解

Nature. 1976 Nov 25;264(5584):370-3. doi: 10.1038/264370a0.

Interferon, double-stranded RNA and RNA degradation. Characteristics of an endonuclease activity.干扰素、双链RNA与RNA降解。一种核酸内切酶活性的特征

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Studies on the mechanism of action of interferon. II. Increased endonuclease activity in extracts from interferon-treated Ehrlich ascites tumour cells: dependence upon ATP and double-stranded RNA [proceedings].干扰素作用机制的研究。II. 经干扰素处理的艾氏腹水瘤细胞提取物中核酸内切酶活性的增加：对ATP和双链RNA的依赖性 [会议论文集]

Arch Int Physiol Biochim. 1977 Feb;85(1):180-1.

Messenger RNA methylation, translation and degradation in extracts of interferon-treated cells.干扰素处理细胞提取物中的信使核糖核酸甲基化、翻译及降解

Tex Rep Biol Med. 1977;35:221-9.

Nuclease activation by double-stranded RNA and by 2',5'-oligoadenylate in extracts of interferon-treated chick cells.双链RNA和2',5'-寡腺苷酸在经干扰素处理的鸡细胞提取物中对核酸酶的激活作用。

Virology. 1979 Mar;93(2):348-56. doi: 10.1016/0042-6822(79)90239-3.

Dual action of double-stranded RNA inhibiting protein synthesis in extracts of interferon-treated mouse L cells. Translation is impaired at the level of initiation and by mRNA degradation.双链RNA在经干扰素处理的小鼠L细胞提取物中抑制蛋白质合成的双重作用。翻译在起始水平受到损害，并通过信使核糖核酸降解。

Eur J Biochem. 1978 May 16;86(2):497-509. doi: 10.1111/j.1432-1033.1978.tb12333.x.

Mechanism of interferon action. Interferon-mediated inhibition of reovirus mRNA translation in the absence of detectable mRNA degradation but in the presence of protein phosphorylation.干扰素作用机制。在未检测到mRNA降解但存在蛋白质磷酸化的情况下，干扰素介导的呼肠孤病毒mRNA翻译抑制。

Virology. 1980 Dec;107(2):461-475. doi: 10.1016/0042-6822(80)90313-x.

Interferon-induced inhibition of protein synthesis in L-cell extracts: an ATP-dependent step in the activation of an inhibitor by double-stranded RNA.干扰素诱导的L细胞提取物中蛋白质合成的抑制：双链RNA激活抑制剂过程中依赖ATP的步骤。

Proc Natl Acad Sci U S A. 1976 Sep;73(9):3136-40. doi: 10.1073/pnas.73.9.3136.

Interferon action: two distinct pathways for inhibition of protein synthesis by double-stranded RNA.干扰素作用：双链RNA抑制蛋白质合成的两条不同途径。

Proc Natl Acad Sci U S A. 1978 Dec;75(12):5893-7. doi: 10.1073/pnas.75.12.5893.

Inhibition of reovirus messenger RNA methylation in extracts of interferon-treated Ehrlich ascites tumor cells.在经干扰素处理的艾氏腹水瘤细胞提取物中呼肠孤病毒信使核糖核酸甲基化的抑制作用

Biochem Biophys Res Commun. 1975 Jul 8;65(1):427-34. doi: 10.1016/s0006-291x(75)80111-2.

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A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.一种新型的 RNase L 抑制机制：Theiler's 病毒 L* 蛋白阻止 2-5A 与 RNase L 结合。

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Wanderings in biochemistry.生物化学漫谈

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Diverse functions of RNase L and implications in pathology.核糖核酸酶L的多种功能及其在病理学中的意义。

Biochimie. 2007 Jun-Jul;89(6-7):789-98. doi: 10.1016/j.biochi.2007.02.006. Epub 2007 Feb 20.

The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation.2-5A系统：通过加速RNA降解来调节病毒和细胞过程。

Pharmacol Ther. 1998 May;78(2):55-113. doi: 10.1016/s0163-7258(97)00167-8.

A study of the interferon antiviral mechanism: apoptosis activation by the 2-5A system.干扰素抗病毒机制的研究：2-5A系统激活细胞凋亡

J Exp Med. 1997 Sep 15;186(6):967-72. doi: 10.1084/jem.186.6.967.

Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.通过呼肠孤病毒S4基因的表达逆转缺乏E3L的痘苗病毒的干扰素敏感表型。

J Virol. 1995 Jan;69(1):499-505. doi: 10.1128/JVI.69.1.499-505.1995.

Double-stranded RNA.双链RNA

Mol Cell Biochem. 1980 Aug 16;31(3):147-64. doi: 10.1007/BF00225848.

X-ray structure of a dinucleoside monophosphate A2'p5'C that contains a 2'-5' link found in (2'-5')oligo(A)s induced by interferons: single-stranded helical conformation of 2'-5'-linked oligonucleotides.一种含有2'-5'连接的二核苷酸单磷酸A2'p5'C的X射线结构，该连接存在于由干扰素诱导产生的(2'-5')寡聚腺苷酸中：2'-5'连接的寡核苷酸的单链螺旋构象。

Proc Natl Acad Sci U S A. 1982 Dec;79(23):7292-6. doi: 10.1073/pnas.79.23.7292.

Interferon inhibits Sendai virus-induced cell fusion: an effect on cell membrane fluidity.

Proc Natl Acad Sci U S A. 1982 Feb;79(3):835-9. doi: 10.1073/pnas.79.3.835.

The interferon renaissance: molecular aspects of induction and action.干扰素的复兴：诱导与作用的分子层面

Microbiol Rev. 1981 Jun;45(2):244-66. doi: 10.1128/mr.45.2.244-266.1981.

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