Vatazin A V, Kruglov E E, Fomin A M, Suslov V P, Koshelev R V, Astakhov P V
Anesteziol Reanimatol. 2002 Mar-Apr(2):73-6.
Selective detoxication of the blood from the portal vein was carried out in 31 patients with peritonitis complicated by multiple organ dysfunction including toxic hepatopathy. Selective extracorporeal detoxication of the blood from the portal vein possesses notable regional hemodynamic advantages in comparison with other variants of vascular approaches and essentially improves the transhepatic bloodflow. The authors emphasize that bifiltration cascade exchange portoplasmapheresis is a method of choice in severe toxic hepatopathy in patients with peritonitis. They recommend alternating bifiltration cascade exchange portoplasmapheresis with portohemofiltration in patients with toxic hepatonephropathy.
对31例并发包括中毒性肝病在内的多器官功能障碍的腹膜炎患者进行了门静脉血液的选择性解毒。与其他血管途径变体相比，门静脉血液的选择性体外解毒具有显著的局部血流动力学优势，并能从根本上改善肝内血流。作者强调，双滤过级联交换门静脉血浆置换术是腹膜炎患者严重中毒性肝病的首选方法。他们建议对中毒性肝肾疾病患者交替进行双滤过级联交换门静脉血浆置换术和门静脉血液滤过。
