Joosten K F, van den Berg S
Afd. Kinder Intensive Care, Academisch Ziekenhuis Rotterdam-Sophia Kinderziekenhuis.
Ned Tijdschr Geneeskd. 1998 Dec 5;142(49):2665-9.
The obstructive sleep apnoea syndrome (OSAS) in children is a clinical syndrome resulting from complete or partial obstruction of the upper respiratory tract during sleep. The pathogenesis is multifactorial; clear risk groups are children with anatomical anomalies of the upper airways, neurological abnormalities and genetic syndromes (including craniofacial syndromes). The clinical symptoms of OSAS in children vary. In partial obstructions, the most frequent forms, the patients may snore and have impaired respiration during sleep. Polysomnography contributes to definite confirmation and specification of the clinical diagnosis. Standard values should be interpreted with respect to age. Adenotonsillectomy is the most frequent treatment of children with OSAS. In persistent symptoms, continuous positive pressure therapy is often successful. The natural evolution and the long-term prognosis of OSAS in children are still unknown.
儿童阻塞性睡眠呼吸暂停综合征(OSAS)是一种睡眠期间上呼吸道完全或部分阻塞导致的临床综合征。其发病机制是多因素的;明确的风险群体是患有上气道解剖异常、神经异常和遗传综合征(包括颅面综合征)的儿童。儿童OSAS的临床症状各不相同。在部分阻塞(最常见的形式)中,患者可能打鼾并在睡眠期间呼吸受损。多导睡眠图有助于明确临床诊断并进行细化。标准值应根据年龄进行解读。腺样体扁桃体切除术是治疗儿童OSAS最常用的方法。对于持续存在症状的情况,持续气道正压通气治疗通常会取得成功。儿童OSAS的自然病程和长期预后仍然未知。