Kaper J B
Center for Vaccine Development,University of Maryland School of Medicine, 685 West Baltimore St., Baltimore, Maryland 21201-1509, USA.
Curr Opin Microbiol. 1998 Feb;1(1):103-8. doi: 10.1016/s1369-5274(98)80149-5.
Enterohemorrhagic Escherichia coli has been responsible for an increasing number of large food-borne outbreaks of bloody diarrhea and hemolytic uremic syndrome. Recent developments in our understanding of the pathogenesis of disease due to enterhemorrhagic E. coli include the description of a pathogenicity island, a type III secretion system and potential plasmid-encoded virulence factors. Recent developments in our understanding of the epidemiology include a recognition of a widening spectrum of vehicles.
肠出血性大肠杆菌已导致越来越多由食物传播的大规模血性腹泻和溶血性尿毒综合征疫情。我们对肠出血性大肠杆菌所致疾病发病机制的最新认识进展包括对一个致病岛、一种III型分泌系统以及潜在质粒编码毒力因子的描述。我们对流行病学的最新认识进展包括认识到传播媒介的范围不断扩大。