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与溶血尿毒综合征暴发相关的肠聚集性、产志贺毒素大肠杆菌O111:H2

Enteroaggregative, Shiga toxin-producing Escherichia coli O111:H2 associated with an outbreak of hemolytic-uremic syndrome.

作者信息

Morabito S, Karch H, Mariani-Kurkdjian P, Schmidt H, Minelli F, Bingen E, Caprioli A

机构信息

Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy.

出版信息

J Clin Microbiol. 1998 Mar;36(3):840-2. doi: 10.1128/JCM.36.3.840-842.1998.

DOI:10.1128/JCM.36.3.840-842.1998
PMID:9508328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC104641/
Abstract

Shiga toxin-producing Escherichia coli O111:H2 strains from an outbreak of hemolytic-uremic syndrome showed aggregative adhesion to HEp-2 cells and harbored large plasmids which hybridized with the enteroaggregative E. coli probe PCVD432. These strains present a novel combination of virulence factors and might be as pathogenic to humans as the classic enterohemorrhagic E. coli.

摘要

一起溶血性尿毒综合征暴发中分离出的产志贺毒素大肠杆菌O111:H2菌株对HEp-2细胞表现出聚集性黏附，并携带与肠聚集性大肠杆菌探针PCVD432杂交的大质粒。这些菌株呈现出毒力因子的新组合，对人类的致病性可能与经典的肠出血性大肠杆菌一样强。

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本文引用的文献

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J Food Prot. 1996 Oct;59(10):1112-1122. doi: 10.4315/0362-028X-59.10.1112.
2
Acute and chronic diarrhoea and abdominal colic associated with enteroaggregative Escherichia coli in young children living in western Europe.西欧幼儿中与肠集聚性大肠杆菌相关的急慢性腹泻及腹部绞痛
Lancet. 1997 Jun 7;349(9066):1660-2. doi: 10.1016/S0140-6736(96)12485-5.
3
A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.从肠致病性大肠杆菌克隆出的一个致病岛赋予了大肠杆菌K-12紧密黏附与抹平样病变表型。
Mol Microbiol. 1997 Jan;23(2):399-407. doi: 10.1046/j.1365-2958.1997.2311591.x.
4
Possible person-to-person transmission of Escherichia coli O111--associated hemolytic uremic syndrome.
Pediatr Nephrol. 1997 Feb;11(1):36-9. doi: 10.1007/s004670050229.
5
Analysis of the enterohemorrhagic Escherichia coli O157 DNA region containing lambdoid phage gene p and Shiga-like toxin structural genes.对含有λ样噬菌体基因p和志贺样毒素结构基因的肠出血性大肠杆菌O157 DNA区域的分析。
Appl Environ Microbiol. 1996 Mar;62(3):791-7. doi: 10.1128/aem.62.3.791-797.1996.
6
KatP, a novel catalase-peroxidase encoded by the large plasmid of enterohaemorrhagic Escherichia coli O157:H7.KatP是一种由肠出血性大肠杆菌O157:H7的大质粒编码的新型过氧化氢酶-过氧化物酶。
Microbiology (Reading). 1996 Nov;142 ( Pt 11):3305-15. doi: 10.1099/13500872-142-11-3305.
7
Characteristics of Escherichia coli strains belonging to enteropathogenic E. coli serogroups isolated in Italy from children with diarrhea.从意大利腹泻儿童中分离出的属于肠致病性大肠杆菌血清群的大肠杆菌菌株的特征
J Clin Microbiol. 1996 Mar;34(3):689-94. doi: 10.1128/jcm.34.3.689-694.1996.
8
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J Clin Microbiol. 1996 Jul;34(7):1622-7. doi: 10.1128/JCM.34.7.1622-1627.1996.
9
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