与溶血尿毒综合征暴发相关的肠聚集性、产志贺毒素大肠杆菌O111:H2
Enteroaggregative, Shiga toxin-producing Escherichia coli O111:H2 associated with an outbreak of hemolytic-uremic syndrome.
作者信息
Morabito S, Karch H, Mariani-Kurkdjian P, Schmidt H, Minelli F, Bingen E, Caprioli A
机构信息
Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy.
出版信息
J Clin Microbiol. 1998 Mar;36(3):840-2. doi: 10.1128/JCM.36.3.840-842.1998.
Abstract
Shiga toxin-producing Escherichia coli O111:H2 strains from an outbreak of hemolytic-uremic syndrome showed aggregative adhesion to HEp-2 cells and harbored large plasmids which hybridized with the enteroaggregative E. coli probe PCVD432. These strains present a novel combination of virulence factors and might be as pathogenic to humans as the classic enterohemorrhagic E. coli.
摘要
一起溶血性尿毒综合征暴发中分离出的产志贺毒素大肠杆菌O111:H2菌株对HEp-2细胞表现出聚集性黏附，并携带与肠聚集性大肠杆菌探针PCVD432杂交的大质粒。这些菌株呈现出毒力因子的新组合，对人类的致病性可能与经典的肠出血性大肠杆菌一样强。
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