Oldstone M B
Division of Virology, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Curr Opin Microbiol. 1998 Aug;1(4):436-41. doi: 10.1016/s1369-5274(98)80062-3.
Recent research has brought additional information on how virus products interfere with host cell antigen processing in vitro, new information on the interaction of virus with dendritic cells as a mechanism for alteration of immune responses - especially immunosuppression, and a preliminary proposal that nonretroviral RNA viruses might persist by utilizing host-cell reverse transcriptase to enter a DNA phase of replication.
最近的研究带来了关于病毒产物如何在体外干扰宿主细胞抗原加工的更多信息,关于病毒与树突状细胞相互作用作为免疫反应改变机制(尤其是免疫抑制)的新信息,以及一项初步提议,即非逆转录RNA病毒可能通过利用宿主细胞逆转录酶进入DNA复制阶段而持续存在。