Schnable P S, Hsia A P, Nikolau B J
Department of Agronomy, lowa State University, Ames, IA 50011, USA.
Curr Opin Plant Biol. 1998 Apr;1(2):123-9. doi: 10.1016/s1369-5266(98)80013-7.
Meiotic recombination generates novel allelic arrays on chromosomes. Recent experiments have revealed an extraordinarily nonrandom distribution of recombination breakpoints along the lengths of plant chromosomes; for example, recombination breakpoints often resolve within genic sequences, and thereby generate novel alleles. The mechanism by which recombination breakpoints are determined is an area of active investigation. In addition, recent developments are providing recombination-based technologies for creating targeted alterations in the architecture of plant genomes.
减数分裂重组在染色体上产生新的等位基因阵列。最近的实验揭示了重组断点沿植物染色体长度的分布极不随机;例如,重组断点常常在基因序列内解析,从而产生新的等位基因。确定重组断点的机制是一个正在积极研究的领域。此外,最近的进展正在提供基于重组的技术,用于在植物基因组结构中进行靶向改变。