Yap K B, Chan K M
Department of Geriatric Medicine, Alexandra Hospital, Singapore.
Singapore Med J. 1998 Nov;39(11):496-500.
There has been no local data on the prescribing habits of doctors over the last 25 years. This is a retrospective study done to examine the outpatient prescribing pattern of doctors at Alexandra Hospital over a one month period in 1995.
Six-thousand five-hundred and three scripts were analysed. A total of 16,642 items were prescribed. The distribution of prescription scripts by departments included Accident & Emergency 39.0%; Medical 23.5%; Orthopaedics 10.3%; Surgery 18.5%; Paediatrics 4.4%, and Geriatrics 4.3%. The overall mean number of drugs prescribed was 2.6 (median = 2, mode = 2, range = 14).
Analysis of the overall results by age groups showed the following means for "total number of drugs prescribed": (> 0 to 20 years) = 2.23, (> 20 to 40 years) = 2.42, (> 40 to 60 years) = 2.61 and (> 60 years) = 3.18. Analysis of variance showed highly significant results between the means of each age-group. Post-hoc analysis revealed that the oldest age group (> 60 years) accounted for most of this significant result. The top 10 drugs used by the hospital were (in descending order): NSAIDs, antacids, analgesics (other than NSAID), antibiotics, topical medications, anti-diarrhoeal agents, anti-histamines, vitamins, anti-emetics and promethazine cough syrup. There was a high usage of NSAID-antacid combination. Similarly, amoxycillin was often given with cloxacillin. There was an underuse of anti-depressants. There were very few (0.15%) illegible prescriptions. Only one prescription had an adverse combination of drugs.
This is the first local study of prescribing pattern of a hospital. While this data may vary from hospital to hospital, depending on the patient mix, it does provide some useful baseline data which hitherto never existed. Our findings suggested that the elderly do receive more medications.
过去25年里,本地没有关于医生处方习惯的数据。这是一项回顾性研究,旨在调查1995年亚历山德拉医院医生在一个月内的门诊处方模式。
分析了6503份处方。共开出16642种药品。按科室划分的处方分布情况为:急诊39.0%;内科23.5%;骨科10.3%;外科18.5%;儿科4.4%,老年病科4.3%。所开药物的总体平均数为2.6(中位数=2,众数=2,范围=1 - 4)。
按年龄组对总体结果进行分析,得出“所开药物总数”的以下平均数:(>0至20岁)=2.23,(>20至40岁)=2.42,(>40至60岁)=2.61,(>60岁)=3.18。方差分析显示各年龄组平均数之间有高度显著差异。事后分析表明,年龄最大的组(>60岁)是造成这一显著差异的主要原因。该医院使用的前10种药物依次为(按降序排列):非甾体抗炎药、抗酸剂、(非甾体抗炎药以外的)镇痛药、抗生素、外用药、止泻药、抗组胺药、维生素、止吐药和异丙嗪止咳糖浆。非甾体抗炎药 - 抗酸剂组合的使用率很高。同样,阿莫西林常与氯唑西林一起使用。抗抑郁药使用不足。难以辨认的处方很少(0.15%)。只有一张处方存在不良药物组合。
这是本地首次对一家医院的处方模式进行研究。虽然这些数据可能因医院而异,取决于患者构成,但它确实提供了一些有用的基线数据,而这些数据以前并不存在。我们的研究结果表明,老年人确实服用了更多药物。