Min B S, Hattori M, Lee H K, Kim Y H
College of Pharmacy, Chungnam National University, Taejon, Korea.
Arch Pharm Res. 1999 Feb;22(1):75-7. doi: 10.1007/BF02976440.
Two diterpenoid compounds, agastanol (1) and agastaquinone (2), were isolated from the roots of Agastache rugosa (Labiatae). Compound 1 and 2 showed significant inhibitory effects against human immunodeficiency virus type 1 (HIV-1) protease activity with IC50 values of 360 and 87 microM, respectively.
从藿香（唇形科）根部分离出两种二萜类化合物，藿香烷醇（1）和藿香醌（2）。化合物1和2对1型人类免疫缺陷病毒（HIV-1）蛋白酶活性表现出显著抑制作用，IC50值分别为360和87微摩尔。
