Stevenson G W, Tobin M, Horn B, Chen E H, Hall S C, Coté C J
Department of Anesthesiology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA.
Anesth Analg. 1999 Mar;88(3):527-30. doi: 10.1097/00000539-199903000-00011.
We compared the efficacy of an adult circle system versus a Bain system to deliver minute ventilation (V(E)) to an infant test lung model using pressure-limited ventilation. To simulate a wide variety of potential infant clinical states, V(E) was measured with two compliances: at peak inspiratory pressures (PIP) of 20, 30, 40, and 50 cm H2O and at respiratory rates (RR) of 20, 30, 40, and 50 breaths/min. Each measurement was made three times, and their average was used for analysis. Data were analyzed using the multiple regression technique. In both normal and low-compliance lung models, V(E) was nearly identical between adult circle and Bain systems (P = 0.67 for normal compliance model, P = 0.89 for low-compliance model). V(E) positively correlated with RR (P < 0.001), PIP (P < 0.001), and lung compliance (P < 0.001). Very high PIP or RR were required to deliver V(E) to the low-compliance lung model. The adult circle system is equivalent to the Bain system in its ability to ventilate an infant test lung over a wide range of RR, PIP, and two compliances during pressure-limited ventilation. V(E) is dependent of PIP, RR, and lung compliance. With low-compliance lungs, both systems require a high PIP. We conclude that both anesthetic systems deliver ventilation over a wide range of respiratory variables during pressure-limited ventilation in infants.
We obtained results from this infant test lung study that indicate that either an adult circle breathing system or the Bain system can reliably deliver ventilation over a wide range of respiratory variables during pressure-limited ventilation in infants.
我们比较了成人循环系统与贝恩系统在使用压力限制通气向婴儿测试肺模型输送分钟通气量(V(E))方面的效果。为模拟各种潜在的婴儿临床状态,在两种顺应性情况下测量V(E):在吸气峰压(PIP)为20、30、40和50 cm H₂O以及呼吸频率(RR)为20、30、40和50次/分钟时。每次测量进行三次,并将其平均值用于分析。使用多元回归技术分析数据。在正常和低顺应性肺模型中,成人循环系统和贝恩系统的V(E)几乎相同(正常顺应性模型P = 0.67,低顺应性模型P = 0.89)。V(E)与RR(P < 0.001)、PIP(P < 0.001)和肺顺应性(P < 0.001)呈正相关。向低顺应性肺模型输送V(E)需要非常高的PIP或RR。在压力限制通气期间,成人循环系统在广泛的RR、PIP和两种顺应性范围内为婴儿测试肺通气的能力与贝恩系统相当。V(E)取决于PIP、RR和肺顺应性。对于低顺应性肺,两个系统都需要高PIP。我们得出结论,在婴儿压力限制通气期间,两种麻醉系统都能在广泛的呼吸变量范围内提供通气。
我们从这项婴儿测试肺研究中获得的结果表明,在婴儿压力限制通气期间,成人循环呼吸系统或贝恩系统都可以在广泛的呼吸变量范围内可靠地提供通气。