Tobin M J, Stevenson G W, Horn B J, Chen E H, Hall S C, Coté C J
Department of Anesthesiology, Children's Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60614, USA.
Anesth Analg. 1998 Oct;87(4):766-71. doi: 10.1097/00000539-199810000-00005.
We examined the efficiency of an adult circle system with adult bellows to deliver minute ventilation (VE) to an infant test lung model. A Narkomed 2B system (North American Drager, Telford, PA) using three modes of ventilator setup were used: A = time-cycled, volume-controlled using bellows excursion to control delivered volume; B = time-cycled, pressure-controlled using inspiratory pressure limit adjustment to control delivered volume; C = time-cycled, pressure-controlled using the inspiratory flow adjustment to control delivered volume. VE was measured with two compliances (normal and low) and four endotracheal tube (ETT) sizes (2.5-, 3.0-, 3.5-, and 4.0-mm inner diameter). VE was measured at peak inspiratory pressures (PIP) of 20, 30, 40 or 50 cm H2O while respiratory rate (RR) was held constant at 20 breaths/min. VE was measured as RR was set at 20, 30, 40, or 50 breaths/min while target PIP was held constant at 20 cm H2O. Data were analyzed using the multiple regression technique. With the low compliance model, VE was nearly identical regardless of the ventilator setup. With the normal compliance model, minor differences in VE were observed, especially at the highest RR and PIP. VE was dependent on RR, PIP, and lung compliance. Overall, the ventilator setup resulted in minor changes in VE. Very high PIPs were required to deliver VE to the low compliance model. ETT size did not affect VE when lung compliance was low; however, smaller ETT size was a factor when test lung compliance was normal, decreasing delivered VE at higher PIP and RR. We conclude that with a Narkomed 2B adult circle system VE is dependent on PIP, RR, and lung compliance, but not on mode of ventilator setup.
The results of this laboratory investigation indicate that when an adult circle system is used during infant anesthesia, the ventilation delivered depends primarily on the respiratory rate, peak inspiratory pressure, and the compliance of the lung being ventilated, rather than on the specific mode of ventilator setup.
我们研究了一种带有成人风箱的成人环路系统向婴儿测试肺模型输送分钟通气量(VE)的效率。使用了一台Narkomed 2B系统(北美德尔格公司,宾夕法尼亚州特尔福德),采用三种通气机设置模式:A = 时间切换、容量控制,利用风箱行程控制输送容量;B = 时间切换、压力控制,通过调整吸气压力极限控制输送容量;C = 时间切换、压力控制,利用吸气流量调整控制输送容量。在两种顺应性(正常和低顺应性)以及四种气管内导管(ETT)尺寸(内径2.5毫米、3.0毫米、3.5毫米和4.0毫米)条件下测量VE。在吸气峰压(PIP)为20、30、40或50厘米水柱时测量VE,同时呼吸频率(RR)保持恒定在20次/分钟。在RR设置为20、30、40或50次/分钟时测量VE,同时目标PIP保持恒定在20厘米水柱。使用多元回归技术分析数据。在低顺应性模型中,无论通气机设置如何,VE几乎相同。在正常顺应性模型中,观察到VE有微小差异,尤其是在最高RR和PIP时。VE取决于RR、PIP和肺顺应性。总体而言,通气机设置导致VE有微小变化。向低顺应性模型输送VE需要非常高的PIP。当肺顺应性低时,ETT尺寸不影响VE;然而,当测试肺顺应性正常时,较小的ETT尺寸是一个影响因素,在较高PIP和RR时会降低输送的VE。我们得出结论,使用Narkomed 2B成人环路系统时,VE取决于PIP、RR和肺顺应性,而不取决于通气机设置模式。
该实验室研究结果表明,在婴儿麻醉期间使用成人环路系统时,输送的通气主要取决于呼吸频率、吸气峰压以及所通气肺的顺应性,而非通气机设置的具体模式。