神经递质表型的转录调控。
Transcriptional control of neurotransmitter phenotype.
作者信息
Goridis C, Brunet J F
机构信息
Laboratoire de Génétique et Physiologie du Développement Developmental Biology Institute of Marseille CNRS/INSERM Université de la Méditerranée AP de Marseille Campus de Luminy, Marseille Cedex 9 France.
出版信息
Curr Opin Neurobiol. 1999 Feb;9(1):47-53. doi: 10.1016/s0959-4388(99)80006-3.
The specification of neurotransmitter phenotype is an important aspect of neuronal fate determination. Recent studies have begun to define essential transcriptional regulators involved in controlling the mode of neurotransmission in vertebrates and invertebrates, and to examine their regulation by cell-extrinsic factors. An emerging concept is that the control of transmitter choice is intimately linked to that of other aspects of the neuronal phenotype.
神经递质表型的特异性是神经元命运决定的一个重要方面。最近的研究已开始明确参与控制脊椎动物和无脊椎动物神经传递模式的关键转录调节因子，并研究细胞外源性因子对它们的调控。一个新出现的概念是，递质选择的控制与神经元表型的其他方面密切相关。
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