Dinarello C A, Gatti S, Bartfai T
Department of Medicine Division of Infectious Diseases University of Colorado Health Sciences Center Denver Colorado 80262 USA.
Curr Biol. 1999 Feb 25;9(4):R147-50. doi: 10.1016/s0960-9822(99)80085-2.
Recent advances have provided evidence that prostaglandin E2 mediates the generation of fever in response to interleukin-1 or lipopolysaccharide and have reinforced the similarities of signaling downstream of these two pyrogens.
近期的研究进展已提供证据表明,前列腺素E2介导机体对白细胞介素-1或脂多糖产生发热反应,并强化了这两种致热原下游信号传导的相似性。