多裂委陵菜中五种新的三萜皂苷。
Five new triterpene saponins from Pulsatilla patens var. multifida.
作者信息
Ye W, Pan G, Zhang Q, Che C T, Wu H, Zhao S
机构信息
Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong.
出版信息
J Nat Prod. 1999 Feb;62(2):233-7. doi: 10.1021/np9802668.
Five new oleanane-type glycosides (1-5), along with two known triterpene saponins, were isolated from the roots of Pulsatilla patens var. multifida (Ranunculaceae). The structures of the new triterpene saponins were elucidated as 3-O-beta-D-glucopyranosyl(1-->2)-beta-D-galactopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester (1), hederagenin 3-O-[beta-D-glucopyranosyl(1-->2)][beta-D-glucopyranosyl(1-->6)]-beta -D-galactopyranoside (2), 3-O-beta-D-glucopyranosyl bayogenin 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta -D-glucopyranosyl ester (3), 3-O-beta-D-glucopyranosyl(1-->2)-beta-D-galactopyranosyl oleanolic acid 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta -D-glucopyranosyl ester (4), and 3-O-[beta-D-glucopyranosyl(1-->2)][beta-D-glucopyranosyl(1-->6)]-beta -D-galactopyranosyl hederagenin 28-O-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl(1-->6)-beta -D-glucopyranosyl ester (5). Structure elucidation was accomplished by 1D and 2D NMR (HMQC, HMBC, and ROESY) methods, FABMS, and hydrolysis.
从多裂白头翁（毛茛科）的根部分离出5个新的齐墩果烷型糖苷（1 - 5）以及两种已知的三萜皂苷。新三萜皂苷的结构经鉴定分别为3 - O-β-D-吡喃葡萄糖基（1→2）-β-D-吡喃半乳糖基常春藤皂苷元28 - O-β-D-吡喃葡萄糖基酯（1）、常春藤皂苷元3 - O-[β-D-吡喃葡萄糖基（1→2）][β-D-吡喃葡萄糖基（1→6）]-β-D-吡喃半乳糖苷（2）、3 - O-β-D-吡喃葡萄糖基石蒜皂苷元28 - O-α-L-鼠李吡喃糖基（1→4）-β-D-吡喃葡萄糖基（1→6）-β-D-吡喃葡萄糖基酯（3）、3 - O-β-D-吡喃葡萄糖基（1→2）-β-D-吡喃半乳糖基齐墩果酸28 - O-α-L-鼠李吡喃糖基（1→4）-β-D-吡喃葡萄糖基（1→6）-β-D-吡喃葡萄糖基酯（4）以及3 - O-[β-D-吡喃葡萄糖基（1→2）][β-D-吡喃葡萄糖基（1→6）]-β-D-吡喃半乳糖基常春藤皂苷元28 - O-α-L-鼠李吡喃糖基（1→4）-β-D-吡喃葡萄糖基（1→6）-β-D-吡喃葡萄糖基酯（5）。通过一维和二维核磁共振（HMQC、HMBC和ROESY）方法、快原子轰击质谱（FABMS）以及水解反应完成了结构鉴定。
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