氡与肺癌：成本效益分析
Radon and lung cancer: a cost-effectiveness analysis.
作者信息
Ford E S, Kelly A E, Teutsch S M, Thacker S B, Garbe P L
机构信息
National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
出版信息
Am J Public Health. 1999 Mar;89(3):351-7. doi: 10.2105/ajph.89.3.351.
OBJECTIVES
This study examined the cost-effectiveness of general and targeted strategies for residential radon testing and mitigation in the United States.
METHODS
A decision-tree model was used to perform a cost-effectiveness analysis of preventing radon-associated deaths from lung cancer.
RESULTS
For a radon threshold of 4 pCi/L, the estimated costs to prevent 1 lung cancer death are about $3 million (154 lung cancer deaths prevented), or $480,000 per life-year saved, based on universal radon screening and mitigation, and about $2 million (104 lung cancer deaths prevented), or $330,000 per life-year saved, if testing and mitigation are confined to geographic areas at high risk for radon exposure. For mitigation undertaken after a single screening test and after a second confirmatory test, the estimated costs are about $920,000 and $520,000, respectively, to prevent a lung cancer death with universal screening and $130,000 and $80,000 per life-year for high risk screening. The numbers of preventable lung cancer deaths are 811 and 527 for universal and targeted approaches, respectively.
CONCLUSIONS
These data suggest possible alternatives to current recommendations.
目的
本研究考察了美国住宅氡检测与减排的通用策略和针对性策略的成本效益。
方法
采用决策树模型对预防氡相关肺癌死亡进行成本效益分析。
结果
对于4皮居里/升的氡阈值，基于普遍的氡筛查与减排，预防1例肺癌死亡的估计成本约为300万美元（预防154例肺癌死亡），或每挽救1个生命年48万美元；如果检测与减排仅限于氡暴露高风险地理区域，则预防1例肺癌死亡的估计成本约为200万美元（预防104例肺癌死亡），或每挽救1个生命年33万美元。对于单次筛查测试后以及第二次确认测试后进行的减排，基于普遍筛查预防1例肺癌死亡的估计成本分别约为92万美元和52万美元，高风险筛查每生命年分别为13万美元和8万美元。普遍方法和针对性方法可预防的肺癌死亡数分别为811例和527例。
结论
这些数据表明了当前建议可能的替代方案。
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