Rietveld P J, van Putten W L, van der Zee J, van Rhoon G C
Department of Radiation Oncology, University Hospital Rotterdam-Daniel den Hoed Cancer Center/Dijkzigt Hospital, The Netherlands.
Int J Radiat Oncol Biol Phys. 1999 Feb 1;43(3):681-7. doi: 10.1016/s0360-3016(98)00443-x.
This report presents the final stage of our program to improve the quality of our superficial hyperthermia treatments. We have already demonstrated that the Lucite cone applicator (LCA), our technically improved water-filled, wave-guide applicator (WGA), is superior to the conventional WGA. The main objective of the present study was to investigate whether the technical improvements of a WGA were reflected in an improved clinical performance, e.g., a better temperature distribution.
Power and temperature analyses were performed retrospectively on 128 treatments of superficially located tumors (less than 4 cm depth). Twenty-three patients were treated alternately with a WGA setup and a LCA setup.
The average power level per antenna in an array was 48 W and 62 W for the WGA and LCA respectively. The average invasively measured temperatures increased by 0.27 degrees C when the LCAs were used. The temperature difference between the center and the periphery of an antenna, averaged over the complete array of antennae, was 0.43 degrees C using WGAs and -0.05 degrees C using LCAs indicating a more uniform heating. The T90 of the invasively measured temperatures remained unchanged (WGA: 39.4 degrees C versus LCA: 39.5 degrees C).
The LCA is now our standard applicator for superficial hyperthermia treatments as it is technically and clinically proven to be superior to the WGA.
本报告介绍了我们提高浅表热疗质量项目的最后阶段。我们已经证明，我们技术改进的充水式波导施源器（WGA）——有机玻璃锥形施源器（LCA），优于传统的WGA。本研究的主要目的是调查WGA的技术改进是否体现在临床性能的改善上，例如更好的温度分布。
对128例浅表肿瘤（深度小于4 cm）治疗进行了功率和温度分析的回顾性研究。23例患者分别交替采用WGA设置和LCA设置进行治疗。
对于WGA和LCA，阵列中每个天线的平均功率水平分别为48 W和62 W。使用LCA时，平均侵入性测量温度升高了0.27℃。在整个天线阵列中，天线中心与周边的平均温差，使用WGA时为0.43℃，使用LCA时为-0.05℃，这表明加热更均匀。侵入性测量温度的T90保持不变（WGA：39.4℃对LCA：39.5℃）。
LCA现在是我们浅表热疗的标准施源器，因为在技术和临床方面都已证明它优于WGA。
