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[大鼠大脑半球衰老的不对称性]

[Asymmetry of aging of the large hemispheres of the rat brain].

作者信息

Klimenko L L, Deev A I, Protasova O V, Fokin V F, Piruzian L A

机构信息

Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia.

出版信息

Biofizika. 1998 Nov-Dec;43(6):1063-5.

Abstract

The dynamics of the accumulation of free-radical oxidation products in the brain hemispheres of rats in rate ontogenesis was studied. Multiphase changes in the concentration of products in the right and left hemispheres in different age groups were registered. Significant differences in the contents of hydroperoxides, Schiff's bases of phospholipids and lipofuscin in brain hemispheres revealed, which correlates with different rate of ageing of hemispheres.

摘要

研究了大鼠大脑半球中自由基氧化产物在发育过程中的积累动态。记录了不同年龄组大鼠左右半球中产物浓度的多相变化。发现大脑半球中氢过氧化物、磷脂席夫碱和脂褐素含量存在显著差异,这与半球不同的衰老速率相关。

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