Famaey J P, Fontaine J, Reuse J
Agents Actions. 1976 Nov;6(6):724-7. doi: 10.1007/BF02026095.
At the optimal concentration of 10 mg/l, vinblastine increases the submaximal contractions of the isolated guinea-pig ileum induced by the following agonists: acetylcholine, histamine, nicotine, angiotensine, prostaglandins E1 and F2alpha (but not serotonine). It also increases the contractions induced by transmural electrical stimulations of the guinea-pig ileum and reverses the inhibitory effect of non-steroidal anti-inflammatory drugs on these electrically-induced contractions.
在最佳浓度为10毫克/升时，长春碱可增强由以下激动剂诱导的离体豚鼠回肠的次最大收缩：乙酰胆碱、组胺、尼古丁、血管紧张素、前列腺素E1和F2α（但不包括血清素）。它还可增强豚鼠回肠经壁电刺激诱导的收缩，并逆转非甾体抗炎药对这些电诱导收缩的抑制作用。
