Basso N, Giri S, Lezoche E, Materia A, Melchiorri P, Speranza V
Am J Gastroenterol. 1976 Nov;66(5):448-51.
The action of duodenal acidification, of continuous I.V. infusion of secretin and glucagon and of a one bolus I.V. administration of secretin and glucagon at maximal doses on BBS-induced gastrin secretion has been studied in a group of 18 healthy subjects. Continuous infusion of secretin and glucagon and the acidification of the duodenum did not alter significantly the levels of gastrin stimulated by BBS. Secretin and glucagon administered by a single I.V. bolus paritially inhibit the effect of BBS on gastrin levels. On the basis of these results it is not possible to affirm or to exclude the possibility that BBS is a hormone physiologically present in man.
在18名健康受试者中，研究了十二指肠酸化、持续静脉输注促胰液素和胰高血糖素以及一次静脉推注最大剂量促胰液素和胰高血糖素对BBS诱导的胃泌素分泌的作用。持续输注促胰液素和胰高血糖素以及十二指肠酸化并未显著改变BBS刺激的胃泌素水平。单次静脉推注促胰液素和胰高血糖素可部分抑制BBS对胃泌素水平的影响。基于这些结果，无法肯定或排除BBS是人体生理存在的一种激素的可能性。
