Brandi L S, Bertolini R, Santini L
Department of Surgery, School of Anaesthesia and Intensive Care, University of Pisa, Italy.
Eur J Anaesthesiol. 1999 Jan;16(1):53-61. doi: 10.1046/j.1365-2346.1999.00428.x.
Oxygen consumption (VO2) measured by indirect calorimetry (Nellcor-Puritan-Bennett 7250; Carlsbad, CA, USA) has been compared with VO2 calculated by the Fick method in 22 volume-controlled ventilated general surgical patients in the early post-operative period. For 198 pairs of measurements, VO2 Fick and VO2 indirect calorimetry correlated significantly (y = 1.00x - 35.8, P = 0.0001, r = 0.77). VO2 indirect calorimetry was 212 +/- 32 mL min-1 and VO2 Fick was 177 +/- 41 mL min-1 (P = 0.0001). The bias was 35 +/- 26 mL min-1. This difference represents 16 +/- 13% of the total body VO2. VO2 calculated by the Fick method did not accurately predict VO2 measured by indirect calorimetry, and the two methods were not interchangeable. VO2 calculated by the Fick method underestimated VO2 as measured by indirect calorimetry by a systematic quantity that could be attributed, in part, to VO2 of the lung. Indirect calorimetry should be the preferred method for measuring total body VO2 in mechanically ventilated surgical patients.
通过间接量热法（Nellcor - Puritan - Bennett 7250；美国加利福尼亚州卡尔斯巴德市）测量的22例普通外科手术后早期接受容量控制通气患者的耗氧量（VO2），已与通过Fick法计算的VO2进行了比较。对于198对测量数据，Fick法计算的VO2与间接量热法测量的VO2显著相关（y = 1.00x - 35.8，P = 0.0001，r = 0.77）。间接量热法测量的VO2为212±32 mL·min-1，Fick法计算的VO2为177±41 mL·min-1（P = 0.0001）。偏差为35±26 mL·min-1。这种差异占全身VO2的16±13%。Fick法计算的VO2不能准确预测间接量热法测量的VO2，这两种方法不可互换。Fick法计算的VO2比间接量热法测量的VO2系统性地低估了一部分，这部分可归因于肺的VO2。在机械通气的外科患者中，间接量热法应是测量全身VO2的首选方法。
