Bolte A L, Voelckel K, Kaleta E F
Institut für Geflügelkrankheiten, Justus-Liebig-Universität Giessen.
Dtsch Tierarztl Wochenschr. 1999 Feb;106(2):62-5.
Newcastle disease (ND) remains to be the worldwide most important infectious disease of poultry. This epizootic is in Germany and many other countries a notifiable disease. Prophylactic vaccination is the major tool for the control of ND in poultry and other birds. Eighty-three ostriches (Struthio camelus) which were kept on farms in Germany were checked for the presence of NDV-specific antibodies. Some of these birds are said to be vaccinated against Newcastle disease. Only some of these ostriches contained antibodies which were measurable in haemagglutination inhibition and virus neutralisation tests. Twenty-three previously unvaccinated ostriches were vaccinated with commercially available vaccines. Both the LaSota live and inactivated oil emulsion vaccines were well tolerated following conjunctival or subcutaneous application, respectively. Neither local nor systemic side reactions were observed. After the vaccinations high antibody titres were detected in hemagglutination inhibition and virus neutralisation tests. A strong correlation between both established methods (r = 0.92; < 0.001) were noted.
新城疫（ND）仍是全球最重要的家禽传染病。在德国和许多其他国家，这种动物流行病属于须申报疾病。预防性疫苗接种是控制家禽和其他鸟类新城疫的主要手段。对德国农场饲养的83只鸵鸟（鸵鸟属）进行了新城疫病毒（NDV）特异性抗体检测。据说其中一些鸟类已接种新城疫疫苗。这些鸵鸟中只有一部分含有可在血凝抑制试验和病毒中和试验中检测到的抗体。对23只先前未接种疫苗的鸵鸟接种了市售疫苗。LaSota活疫苗和灭活油乳剂疫苗分别通过结膜或皮下接种后耐受性良好。未观察到局部或全身不良反应。接种疫苗后，在血凝抑制试验和病毒中和试验中检测到高抗体滴度。两种既定方法之间存在很强的相关性（r = 0.92；<0.001）。
