Sorahan T, Hamilton L, Gardiner K, Hodgson J T, Harrington J M
Institute of Occupational Health, University of Birmingham, Edgbaston, United Kingdom.
Am J Ind Med. 1999 Apr;35(4):348-57. doi: 10.1002/(sici)1097-0274(199904)35:4<348::aid-ajim5>3.0.co;2-x.
The concern that maternal exposure to electromagnetic fields (EMF) might be related to childhood cancer risks, particularly leukemia risks.
Maternal occupational data already collected as part of the Oxford Survey of Childhood Cancers have been reviewed. Information on occupations held before, during, and after the pregnancy was sought for 15,041 children dying of cancer in Great Britain in the period 1953-1981, and for an equal number of matched controls. Each period of working was classified under one of five headings: (1) sewing machinist; (2) textile industry workers (other than sewing machinists) with likely exposures to EMF; (3) other machinists and other jobs with likely "higher" EMF exposure; (4) other jobs with likely exposure to some EMF, and (5) jobs with little potential for EMF exposure.
Relative to risks in the children of mothers who held occupations with little potential for EMF exposure during pregnancy (a category that included housewives), risks of all childhood cancers were close to unity both for the children of sewing machinists (22 case and 31 control mothers, RR 0.72, 95% CI 0.42 to 1.25) and for the children of other machinists with likely "higher" EMF exposures (44 case and 47 control mothers, RR 0.93, 95% CI 0.61 to 1.41). Corresponding risks for all childhood leukemias and for all childhood brain cancers were similarly unexceptional. Simultaneous adjustment for social class, maternal age at birth of child, and sibship position had little effect.
The study findings did not indicate that maternal occupational exposure to EMF during pregnancy is a risk factor for childhood leukemias, childhood brain cancers, or the generality of all childhood cancers.
人们担心母亲暴露于电磁场（EMF）可能与儿童癌症风险，尤其是白血病风险有关。
对作为牛津儿童癌症调查一部分已经收集的母亲职业数据进行了回顾。针对1953年至1981年期间在英国死于癌症的15041名儿童以及数量相等的匹配对照，收集了她们在怀孕前、怀孕期间和怀孕后的职业信息。每个工作阶段被归类到以下五个类别之一：（1）缝纫机操作工；（2）可能暴露于电磁场的纺织业工人（不包括缝纫机操作工）；（3）其他机械工以及其他可能“更高”电磁场暴露的工作；（4）其他可能暴露于某些电磁场的工作；（5）几乎没有电磁场暴露可能性的工作。
与怀孕期间从事几乎没有电磁场暴露可能性职业的母亲（包括家庭主妇）的孩子相比，缝纫机操作工的孩子（22例病例和31例对照母亲，RR 0.72，95%CI 0.42至1.25）以及其他可能有“更高”电磁场暴露的机械工的孩子（44例病例和47例对照母亲，RR 0.93，95%CI 0.61至1.41）患所有儿童癌症的风险均接近1。所有儿童白血病和所有儿童脑癌的相应风险同样无异常。同时对社会阶层、孩子出生时母亲的年龄和出生顺序进行调整，影响不大。
研究结果并未表明母亲在怀孕期间职业性暴露于电磁场是儿童白血病、儿童脑癌或所有儿童癌症总体的风险因素。
