Kemmler G, Meise U, Tasser A, Liensberger D, Schifferle I, Braitenberg M, Schwitzer J, Hinterhuber H
Universitätsklinik für Psychiatrie, A-Innsbruck.
Psychiatr Prax. 1999 Jan;26(1):9-15.
In a cross-sectional study in 79 schizophrenic patients the quality of life (QOL) of a group of community-based patients under supervision of an outpatient unit (n = 47) and a group of long-stay patients in an inpatient rehabilitation centre in the same area (n = 32) was compared.
The patients' QOL was evaluated using the Lancashire Quality of Life Profile. Moreover psychopathology and extrapyramidal-motoric side-effects were assessed.
Long-stay patients had a more distinct psychopathological symptomatology and more severe side-effects than community-based patients. After adjustment for psychopathology and side-effects, the subjective QOL of long-stay patients was significantly reduced in two out of eight life domains: housing and leisure activities. While psychopathology was negatively correlated with QOL, a subgroup with very marked psychopathology showed unexpectedly high QOL ratings.
Results suggest that psychopathology is a stronger predictor of subjective QOL than side-effects and treatment setting. Patients with very distinct psychopathology probably use lower standards than others when evaluating their QOL which should be taken into consideration when analysing this type of data.
在一项针对79例精神分裂症患者的横断面研究中,比较了一组在门诊单元监管下的社区患者(n = 47)和同一地区住院康复中心的一组长期住院患者(n = 32)的生活质量(QOL)。
使用兰开夏生活质量量表评估患者的生活质量。此外,还评估了精神病理学和锥体外系运动副作用。
长期住院患者比社区患者有更明显的精神病理症状和更严重的副作用。在对精神病理学和副作用进行调整后,长期住院患者的主观生活质量在八个生活领域中的两个领域显著降低:住房和休闲活动。虽然精神病理学与生活质量呈负相关,但一个精神病理学非常明显的亚组显示出意外高的生活质量评分。
结果表明,精神病理学比副作用和治疗环境更能预测主观生活质量。精神病理学非常明显的患者在评估其生活质量时可能使用比其他人更低的标准,在分析这类数据时应考虑到这一点。