Becker Thomas, Leese Morven, Krumm Silvia, Ruggeri Mirella, Vázquez-Barquero José Luis
Dept. of Psychiatry II, University of Ulm, Ludwig-Heilmeyer-Strasse 2, 89312, Günzburg, Germany.
Soc Psychiatry Psychiatr Epidemiol. 2005 Aug;40(8):628-34. doi: 10.1007/s00127-005-0937-7. Epub 2005 Aug 17.
Global assessment of functioning, quality of life (QOL) and patient needs have been discussed as inter-related domains important for care planning and outcome assessment in care for the severely mentally ill. The study was conducted to investigate relationships of functioning level, subjective QOL and unmet needs in a cross-sectional study of 404 patients with schizophrenia spectrum disorders in five European centres with a focus on the patient group with low function scores.
Patient groups with low, medium and high function scores were compared with regard to subjective QOL and unmet needs. QOL variability was assessed in subgroups according to function scores. Regression analyses were used to examine the impact of illness-related and other unmet patient needs on QOL. The influence of individual needs in the low and medium/high function score subgroup was compared.
QOL increased and unmet needs decreased from the low to high function score subgroup. There was greater QOL variability in patients with low function scores compared to those with medium and high function scores, with some low-function score patients having relatively high QOL. In the low function score subgroup, both illness-related and other needs had an impact on QOL, whereas non-illness needs influenced QOL in medium and high function score patients.
Scores of functioning level, in people with schizophrenia spectrum disorders, are related to QOL in a complex way, and types of unmet need impinge on the relationship. In order to improve QOL in people with low function scores, both illness-related and other needs should be met.
功能的整体评估、生活质量（QOL）和患者需求已被视为相互关联的领域，对严重精神疾病患者的护理规划和结果评估至关重要。本研究旨在对欧洲五个中心的404例精神分裂症谱系障碍患者进行横断面研究，以调查功能水平、主观生活质量和未满足需求之间的关系，重点关注功能评分较低的患者群体。
比较功能评分低、中、高的患者组在主观生活质量和未满足需求方面的差异。根据功能评分对亚组的生活质量变异性进行评估。采用回归分析来检验疾病相关和其他未满足的患者需求对生活质量的影响。比较低功能评分亚组和中/高功能评分亚组中个体需求的影响。
从低功能评分亚组到高功能评分亚组，生活质量提高，未满足需求减少。与功能评分中等和高的患者相比，功能评分低的患者生活质量变异性更大，一些低功能评分患者的生活质量相对较高。在低功能评分亚组中，疾病相关需求和其他需求均对生活质量有影响，而在功能评分中等和高的患者中，非疾病需求影响生活质量。
精神分裂症谱系障碍患者的功能水平评分与生活质量以复杂的方式相关，未满足需求的类型影响这种关系。为了提高低功能评分患者的生活质量，应同时满足疾病相关需求和其他需求。
