Langefeld S, Kirchhof B, Meinert H, Roy T, Aretz A, Schrage N F
Augenklinik der RWTH Aachen, Germany.
Graefes Arch Clin Exp Ophthalmol. 1999 Mar;237(3):201-6. doi: 10.1007/s004170050219.
This study was performed to ascertain the efficacy of Perfluorhexyl-octan, C14F13H17 (F6H8), in dissolving silicone oil from the surface of silicone intraocular lenses. So far F6H8 is the only solvent of silicone oil that is tolerated by intraocular tissues.
Intraocular silicone lenses (Domilens) were examined after application of small droplets of silicone oil of two different viscosities (AdatoSIL-OL 1000 and 5000) followed by rinsing with F6H8. To allow distinction between silicone oil and F6H8 the silicone oil was stained. Microscopic examination was carried out under video control.
One hundred microliters of AdatoSIL-OL 1000 could be easily removed with about 800 microl of F6H8; 50 microl of AdatoSIL-OL 5000 also disappeared after 800 microl of F6H8. A larger drop of the latter oil could not be removed even after application of 2 ml of F6H8.
Silicone oil 1000 can be easily dissolved by F6H8, whereas silicone oil 5000 is more difficult to remove because of its higher viscosity.
本研究旨在确定全氟己基辛烷（C14F13H17，F6H8）溶解硅水凝胶人工晶状体表面硅油的效果。到目前为止，F6H8是眼内组织能够耐受的唯一一种硅油溶剂。
在应用两滴不同粘度（AdatoSIL - OL 1000和5000）的硅油后，用F6H8冲洗，对眼内硅水凝胶晶状体（Domilens）进行检查。为区分硅油和F6H8，对硅油进行了染色。在视频控制下进行显微镜检查。
约800微升的F6H8可轻松去除100微升的AdatoSIL - OL 1000；800微升的F6H8作用后，50微升的AdatoSIL - OL 5000也消失了。即使使用2毫升F6H8，也无法去除较大一滴的后一种硅油。
F6H8可轻松溶解1000粘度的硅油，而5000粘度的硅油因其粘度较高更难去除。
