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Subcellular distribution of a gonadotropin-induced form of mouse ovarian alkaline phosphatase.

作者信息

Bramley T A

出版信息

Biochim Biophys Acta. 1976 Nov 18;451(1):118-23. doi: 10.1016/0304-4165(76)90263-4.

DOI:10.1016/0304-4165(76)90263-4
PMID:1009101
Abstract

The subcellular distributions of alkaline phosphates I (the major activity of prepubertal mouse ovaries) and alkaline phosphatase Ib (a kinetically distinct isoenzyme induced in large amounts by injection of human chorionic gonadotropin or luteinizing hormone) were studied by differential rate centrifugation and discontinuous density gradient centrifugation of ovarian homogenates from control and gonadotropin-treated mice. The distributions of the two alkaline phosphatases were alike and were similar to those of nucleotidase, Mg2+ -dependent ATPase and Co2+ -stimulated naphthylamidase activities, suggesting that they were associated with plasma-membrane vesicles.

摘要

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