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咖啡二萜成分咖啡醇升高胆固醇作用的潜在机制。

Possible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestol.

作者信息

de Roos B, Katan M B

机构信息

Division of Human Nutrition and Epidemiology, Wageningen Centre for Food Sciences, The Netherlands.

出版信息

Curr Opin Lipidol. 1999 Feb;10(1):41-5. doi: 10.1097/00041433-199902000-00008.

Abstract

Cafestol, a coffee diterpene present in unfiltered coffee brews, potently raises serum lipids in humans. The mechanism through which this dietary compound influences liporotein metabolism is largely unknown. Unravelling the mechanism of action might lead to new insights into the regulation of serum cholesterol levels in humans. This review summaries ways in which cafestol may act on serum lipids.

摘要

咖啡醇是一种存在于未过滤咖啡冲泡液中的咖啡二萜,能显著提高人体血清脂质水平。这种膳食化合物影响脂蛋白代谢的机制在很大程度上尚不清楚。阐明其作用机制可能会为人类血清胆固醇水平的调节带来新的见解。这篇综述总结了咖啡醇可能作用于血清脂质的方式。

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