Panagiotakos Demosthenes B, Lionis Christos, Zeimbekis Akis, Makri Kornilia, Bountziouka Vassiliki, Economou Mary, Vlachou Ioanna, Micheli Mary, Tsakountakis Nikos, Metallinos George, Polychronopoulos Evangelos
Department of Nutrition and Dietetics, Harokopio University, Athens, Greece.
Rev Diabet Stud. 2007 Summer;4(2):105-11. doi: 10.1900/RDS.2007.4.105. Epub 2007 Aug 10.
We evaluated the association between coffee drinking and the prevalence of type 2 diabetes mellitus in elderly people from the Mediterranean islands.
During 2005-2007, 500 men and 437 women (aged 65 to 100 years) from the islands of Cyprus (n = 300), Mitilini (n = 142), Samothraki (n = 100), Cephalonia (n = 104), Corfu (n = 160) and Crete (n = 131) participated in the survey. Cardiovascular disease (CVD) risk factors (i.e. hypertension, diabetes, hypercholesterolemia and obesity), as well as behavioral, lifestyle and dietary characteristics were assessed using face-to-face interviews and standard procedures. Among various factors, fasting blood glucose was measured and prevalence of type 2 diabetes mellitus was estimated, according to the established American Diabetes Association (ADA) criteria, while all participants were asked about the frequency of any type of coffee consumption over the last year.
Coffee drinking was reported by 84% of the participants, the majority of whom drank boiled coffee. The participants reported that they had consumed coffee for at least 30 years of their life. Data analysis adjusted for various potential confounders, revealed that, compared to non-consumption, the multi-adjusted odds ratio for having diabetes was 0.47 (95%, CI 0.32 to 0.69) for 1-2 cups/day, while it was 1.05 (95%, CI 0.70 to 1.55) for >3 cups/day, after adjusting for various potential confounders. The association of coffee drinking with diabetes was significant only among non-tea drinkers. Increased coffee intake was not associated with diabetes prevalence.
The data presented suggest that moderate coffee drinking is associated with a lower likelihood of having diabetes, after adjusting for various potential confounders.
我们评估了地中海岛屿老年人咖啡饮用与2型糖尿病患病率之间的关联。
在2005年至2007年期间,来自塞浦路斯岛(n = 300)、米蒂利尼岛(n = 142)、萨莫色雷斯岛(n = 100)、凯法利尼亚岛(n = 104)、科孚岛(n = 160)和克里特岛(n = 131)的500名男性和437名女性(年龄在65至100岁之间)参与了该调查。使用面对面访谈和标准程序评估心血管疾病(CVD)风险因素(即高血压、糖尿病、高胆固醇血症和肥胖症)以及行为、生活方式和饮食特征。在各种因素中,测量空腹血糖,并根据既定的美国糖尿病协会(ADA)标准估计2型糖尿病的患病率,同时询问所有参与者过去一年中任何类型咖啡的饮用频率。
84%的参与者报告饮用咖啡,其中大多数饮用煮咖啡。参与者报告他们一生中至少饮用咖啡30年。对各种潜在混杂因素进行调整后的数据分析显示,与不饮用咖啡相比,每天饮用1 - 2杯咖啡的人群在多因素调整后的糖尿病患病比值比为0.47(95%可信区间为0.32至0.69),而每天饮用超过3杯咖啡的人群该比值比为1.05(95%可信区间为0.70至1.55),在调整各种潜在混杂因素后。咖啡饮用与糖尿病的关联仅在不饮茶者中显著。咖啡摄入量增加与糖尿病患病率无关。
所呈现的数据表明,在调整各种潜在混杂因素后,适度饮用咖啡与患糖尿病的可能性较低相关。