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[内质网和线粒体作为神经元细胞内信号传导机制的组成部分]

[Endoplasmic reticulum and mitochondria as elements of mechanism of intracellular signaling in neurons].

作者信息

Kostiuk P G, Shmigol' A V, Voĭtenko N V, Svichar N V, Kostiuk E P

机构信息

A. A. Bogomolets Institute of Physiology, Ukrainian Acad. Sci., Kiev.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1998 Oct;84(10):979-84.

Abstract

The temporal and spatial characteristics of a transitory increase in free Ca2+ ("calcium signals") concentration were determined in various types of the mice and rat neurones. Intracellular structures: endoplasmatic reticulum and mitochondria, were shown to play a major part in formation of these signals, the structures being able to absorb the Ca2+ ions from cytosol and release them back. The contribution of these processes proves rather varying depending on internal organisation and functional assignment of a neurone.

摘要

在不同类型的小鼠和大鼠神经元中,测定了游离Ca2+(“钙信号”)浓度短暂升高的时空特征。细胞内结构:内质网和线粒体,在这些信号的形成中起主要作用,这些结构能够从细胞质中吸收Ca2+离子并将其释放回去。这些过程的贡献因神经元的内部组织和功能分配而异。

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