Westling L, Mohlin B, Bresin A
Department of Stomatognathic Physiology, Faculty of Odontology, Göteborg University, Sweden.
J Craniofac Genet Dev Biol. 1998 Oct-Dec;18(4):211-8.
The purpose of this study was to determine how the craniofacial morphology, evaluated from dental casts and lateral cephalograms, in individuals affected by the Marfan syndrome diverge from healthy control groups. The high and narrow palatal vault as well as maxillary and mandibular retrognathy were strongly correlated to the syndrome. About 70% of the Marfan syndrome patients (n = 76) had been referred for orthodontic treatment, mostly because of crowded teeth or extreme maxillary overjet. In 36%, the orthodontic treatment was carried out before diagnosis or suspicion about the Marfan syndrome. In comparison to healthy orthodontic patients (n = 86), selected because of presence of high and narrow palatal vaults, crowding of teeth, extreme maxillary overjet, and open bite were much more prevalent in the Marfan syndrome patients than in the orthodontic control group.
本研究的目的是确定从石膏模型和头颅侧位片评估的马凡综合征患者的颅面形态与健康对照组有何不同。高而窄的腭穹窿以及上颌和下颌后缩与该综合征密切相关。约70%的马凡综合征患者（n = 76）因牙齿拥挤或上颌前突过大而被转诊接受正畸治疗。36%的患者在诊断或怀疑患有马凡综合征之前就已接受正畸治疗。与因高而窄的腭穹窿、牙齿拥挤、上颌前突过大和开咬而入选的健康正畸患者（n = 86）相比，马凡综合征患者中这些问题比正畸对照组更为普遍。
