一例伴有严重神经系统表现的幼儿急疹中人类疱疹病毒7型的神经侵袭
Neuroinvasion by human herpesvirus type 7 in a case of exanthem subitum with severe neurologic manifestations.
作者信息
van den Berg J S, van Zeijl J H, Rotteveel J J, Melchers W J, Gabreëls F J, Galama J M
机构信息
Department of Child Neurology, University Hospital Nijmegen, The Netherlands.
出版信息
Neurology. 1999 Mar 23;52(5):1077-9. doi: 10.1212/wnl.52.5.1077.
A 19-month-old girl presented with severe neurologic symptoms associated with exanthem subitum. Human herpesvirus type 7 (HHV-7) DNA was detected in the CSF and serum, and supported by serologic studies. The patient was diagnosed with encephalopathy due to an acute HHV-7 infection. Neuron-specific enolase in the CSF was strongly elevated during the acute stage of infection, suggesting that the encephalopathy was due to viral invasion of the brain.
一名19个月大的女童出现与幼儿急疹相关的严重神经症状。在脑脊液和血清中检测到7型人类疱疹病毒（HHV-7）DNA，并得到血清学研究的支持。该患者被诊断为急性HHV-7感染所致的脑病。在感染急性期，脑脊液中的神经元特异性烯醇化酶显著升高，提示脑病是由病毒侵袭大脑所致。
Zotero 插件