Earley E M, Finley S C, Finley W H, Hsu L Y, Kim H J, Petricciani J C, Vinson P C
In Vitro. 1976 Sep;12(9):639-42. doi: 10.1007/BF02797463.
Cell cultures were established from the biopsies of lung, skin and kidney from each of nine human fetuses, and chromosome analyses were performed on material through the fifth subculture. Kidney cell cultures generally showed a higher level of polyploidy than lung or skin. The frequencies of hyperdiploid cells and those with structural abnormalities were consistent with the low levels found in cultures of human lymphocytes. The data provide a normal cytogenetic baseline for human fetal material which may be useful in a variety of studies.
从9例人类胎儿的肺、皮肤和肾脏活检组织中建立了细胞培养物，并对传代至第五代的材料进行了染色体分析。肾脏细胞培养物中的多倍体水平通常高于肺或皮肤。超二倍体细胞和结构异常细胞的频率与人类淋巴细胞培养物中发现的低水平一致。这些数据为人类胎儿材料提供了一个正常的细胞遗传学基线，可能在各种研究中有用。
