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无菌新生仔猪实验性诱导腹泻时人类呼肠孤病毒样病原体的排毒模式

Patterns of shedding of human reovirus-like agent in gnotobiotic newborn piglets with experimentally-induced diarrhea.

作者信息

Torres-Medina A, Wyatt R G, Mebus C A, Underdahl N R, Kapikian A Z

出版信息

Intervirology. 1976;7(4-5):250-55. doi: 10.1159/000149957.

DOI:10.1159/000149957
PMID:1010712
Abstract

Virus shedding patterns of neonatal gnotobiotic piglets infected with the reovirus-like agent of human infantile gastroenteritis were studied. Fecal viral counts were highest before or at the onset of diarrhea. In diarrheic piglets, viral particles were usually observed for only 1-2 days after the onset of diarrhea, and total duration of shedding was 2-6 days. One infected piglet shed virus for 4 days but did not develop diarrhea. The presence of virus at or about the time of illness is consistent with the induction of diarrhea in piglets inoculated with the human reovirus-like agent.

摘要

对感染人类婴儿肠胃炎类呼肠孤病毒的新生无菌仔猪的病毒排出模式进行了研究。粪便病毒计数在腹泻前或腹泻开始时最高。在腹泻仔猪中,腹泻开始后通常仅在1-2天内观察到病毒颗粒,病毒排出的总持续时间为2-6天。一头感染的仔猪排出病毒4天,但未出现腹泻。在发病时或发病前后存在病毒与接种人类类呼肠孤病毒的仔猪腹泻的诱导一致。

相似文献

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Patterns of shedding of human reovirus-like agent in gnotobiotic newborn piglets with experimentally-induced diarrhea.无菌新生仔猪实验性诱导腹泻时人类呼肠孤病毒样病原体的排毒模式
Intervirology. 1976;7(4-5):250-55. doi: 10.1159/000149957.
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J Clin Microbiol. 1976 Mar;3(3):376-7. doi: 10.1128/jcm.3.3.376-377.1976.

引用本文的文献

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Infect Immun. 1984 Mar;43(3):906-11. doi: 10.1128/iai.43.3.906-911.1984.
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Scanning electron microscopy of intestine of gnotobiotic piglets infected with porcine rotavirus.对感染猪轮状病毒的无菌仔猪肠道进行扫描电子显微镜检查。
Can J Comp Med. 1980 Oct;44(4):403-11.
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Diarrheal response of gnotobiotic pigs after fetal infection and neonatal challenge with homologous and heterologous human rotavirus strains.
无菌仔猪经同源和异源人轮状病毒株胎儿感染及新生儿攻击后的腹泻反应
J Virol. 1986 Dec;60(3):1107-12. doi: 10.1128/JVI.60.3.1107-1112.1986.
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Gastroenterology. 1991 Oct;101(4):895-901. doi: 10.1016/0016-5085(91)90713-u.
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Epidemic viral gastroenteritis.流行性病毒性胃肠炎
Am J Med. 1979 Jun;66(6):1001-7. doi: 10.1016/0002-9343(79)90457-1.