Thornsberry C, Jaffe H W, Reynolds G H, Zaidi A A, Wiesner P J
Antimicrob Agents Chemother. 1978 Sep;14(3):327-30. doi: 10.1128/AAC.14.3.327.
In an ongoing cooperative study of uncomplicated genital gonorrhea within the United States, 6,735 pretreatment gonococcal isolates were tested for their in vitro resistance to penicillin. By using a regression analysis technique, we examined 99 patient-associated variables which might be associated with penicillin resistance of the isolates. Patients were most likely to have relatively resistant isolates if they were black, had used antimicrobial agents within 2 weeks of treatment for gonorrhea, or were men with symptomatic urethritis.
在美国一项正在进行的单纯性生殖器淋病合作研究中,对6735株治疗前淋球菌分离株进行了青霉素体外耐药性检测。通过回归分析技术,我们检查了99个可能与分离株青霉素耐药性相关的患者相关变量。如果患者是黑人、在淋病治疗前2周内使用过抗菌药物或者是有症状性尿道炎的男性,则其分离株最有可能具有相对耐药性。