头孢尼西作为产青霉素酶淋病奈瑟菌所致单纯性淋菌性尿道炎的治疗药物。
Cefonicid as therapy for uncomplicated gonococcal urethritis caused by penicillinase-producing Neisseria gonorrhoeae.
作者信息
Sanchez P L, Lancaster D J, Berg S W, Kerbs S B, Harrison W O
出版信息
West J Med. 1984 Feb;140(2):224-6.
Young men with uncomplicated gonococcal urethritis were treated with 1 gram of cefonicid given intramuscularly plus 1 gram of probenecid by mouth. Of 53 evaluable patients, 33 (62%) had penicillinase-producing Neisseria gonorrhoeae. All but one of these patients were cured. All men who had penicillin-sensitive infections were cured. Cefonicid was highly effective in the treatment of both penicillin-sensitive and penicillin-resistant N gonorrhoeae. Other than moderate pain at the site of injection, there were no adverse side effects. Cefonicid can be added to the group of newer cephalosporins that are effective in the treatment of gonococcal urethritis caused by either penicillin-sensitive or penicillin-resistant strains.
患有单纯性淋菌性尿道炎的年轻男性接受了肌肉注射1克头孢尼西加口服1克丙磺舒的治疗。在53例可评估的患者中，33例（62%）感染了产青霉素酶的淋病奈瑟菌。除1例患者外，所有这些患者均治愈。所有感染青霉素敏感菌的男性均治愈。头孢尼西在治疗青霉素敏感和耐青霉素淋病奈瑟菌方面都非常有效。除注射部位有中度疼痛外，无其他不良反应。头孢尼西可加入到对由青霉素敏感或耐青霉素菌株引起的淋菌性尿道炎有效的新型头孢菌素组中。
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