Gutteridge B, Torrie P, Galland B
Prospect Park Hospital, Reading.
Health Trends. 1994;26(3):88-91.
Data from operating theatre and X-ray department ledgers, and other sources, for two periods (1983-87 and 1988-91) were compared retrospectively to determine the trend in leg amputation in the defined population of a District Health Authority, following an increase in arterial reconstruction and percutaneous transluminal angioplasty for peripheral arterial disease. There was an eleven-fold increase in arterial reconstructions, and a thirteen-fold increase in angioplasty, in 1988-1991 compared with 1983-1987. A significant reduction occurred in the age- and sex-adjusted mean annual rate for major leg amputation, from 47.5 (95% confidence intervals 41.5-53.6) in 1983-87 to 32 (95% confidence intervals 26.5-37.6) in 1988-91 (Wilcoxon rank sum test, p < 0.05). There was no increase in the ratio of above-knee to below-knee amputations. The introduction of peripheral arterial reconstruction and percutaneous transluminal angioplasty was associated with a reduction in major amputations for peripheral arterial disease of 3.8 per 100,000 population per year.
对手术室和X光科室分类账以及其他来源的数据进行回顾性比较，这些数据来自两个时期（1983 - 1987年和1988 - 1991年），目的是确定在一个地区卫生管理局规定人群中，随着外周动脉疾病的动脉重建和经皮腔内血管成形术增加后，腿部截肢的趋势。与1983 - 1987年相比，1988 - 1991年动脉重建增加了11倍，血管成形术增加了13倍。经年龄和性别调整后的主要腿部截肢年平均率显著降低，从1983 - 1987年的47.5（95%置信区间41.5 - 53.6）降至1988 - 1991年的32（95%置信区间26.5 - 37.6）（Wilcoxon秩和检验，p < 0.05）。膝上截肢与膝下截肢的比例没有增加。外周动脉重建和经皮腔内血管成形术的引入使外周动脉疾病导致的主要截肢每年每10万人减少3.8例。
