Küchle M
University Erlangen-Nürnberg, Germany.
Curr Opin Ophthalmol. 1994 Aug;5(4):110-6.
Laser tyndallometry refers to in vivo quantification of aqueous flare by measuring the scatter of a laser beam that is scanned into the anterior chamber. The laser flare-cell meter was introduced in 1988 and allows noninvasive, reproducible tyndallometry. Because biochemical studies have shown that the amount of laser light scattering correlates with aqueous protein concentration, laser tyndallometry allows noninvasive analysis of the integrity of the blood-aqueous barrier. Laser tyndallometry has been mainly applied to uveitis and to postoperative anterior segment changes with many of studies focusing on the anti-inflammatory effects of postoperative medications. In addition, the method was shown to give valuable information on the integrity of the blood-aqueous barrier in ocular and systemic diseases including diabetic retinopathy and pseudoexfoliation syndrome, in eyes with graft rejection after penetrating keratoplasty, and in various disease processes that mainly affect the posterior segment including retinitis pigmentosa, retinal vein occlusion, and uveal melanoma.
激光丁达尔ometry是指通过测量扫描进入前房的激光束的散射来对房水闪光进行体内定量。激光闪光细胞仪于1988年推出，可进行无创、可重复的丁达尔ometry测量。由于生化研究表明激光散射量与房水蛋白质浓度相关，激光丁达尔ometry可对血-房水屏障的完整性进行无创分析。激光丁达尔ometry主要应用于葡萄膜炎和术后眼前节变化，许多研究聚焦于术后药物的抗炎作用。此外，该方法还被证明能提供有关眼部和全身性疾病（包括糖尿病视网膜病变和假性剥脱综合征）、穿透性角膜移植术后发生移植排斥反应的眼睛以及主要影响后节的各种疾病过程（包括视网膜色素变性、视网膜静脉阻塞和葡萄膜黑色素瘤）中血-房水屏障完整性的有价值信息。
