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[视觉功能丧失与恢复的若干生化指标]

[Several biochemical signs of loss and restoration of visual function].

作者信息

Busniuk M M

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976 Dec;76(12):1806-10.

PMID:1015117
Abstract

With the aid of cytophotometry the author studied the cellular chemistry of neurons (according to the activity of glutamate dehydrogenase) in the III, IV and V layers of the visual cortex in rats during the period of rehabilitation of specific functions following long-term light deprivation. It was demonstrated that a 2-week stay of deprivated animals in conditions of usual light is accompanied by visible normalization of the glutamate dehydrogenase activity in the cortical neurons. However, a complete rehabilitation of the control level was not attained. The study demonstrated differences in the reactions of identical neurons in the IV and V layers to the rehabilitation of specific functions. It is being assumed that the rehabilitation of the visual function may be due to biochemical reconstructions in the monomodel and certain parts of the polymodal neurons in the visual cortex.

摘要

借助细胞光度测量法,作者研究了长期光照剥夺后特定功能恢复期间大鼠视觉皮层第III、IV和V层神经元的细胞化学(根据谷氨酸脱氢酶的活性)。结果表明,剥夺光照的动物在正常光照条件下饲养2周,其皮层神经元中谷氨酸脱氢酶活性明显恢复正常。然而,并未达到对照水平的完全恢复。研究表明,第IV和V层相同神经元对特定功能恢复的反应存在差异。据推测,视觉功能的恢复可能归因于视觉皮层单模式和多模式神经元某些部分的生化重建。

相似文献

1
[Several biochemical signs of loss and restoration of visual function].[视觉功能丧失与恢复的若干生化指标]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976 Dec;76(12):1806-10.
2
[Glutamate dehydrogenase activity in motor cortex neurons during restoration of disrupted visual function].[视觉功能受损恢复过程中运动皮层神经元的谷氨酸脱氢酶活性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1979 Sep-Oct;29(5):1061-6.
3
[Biochemical correlates of functional features of visual cortex neurons].[视觉皮层神经元功能特征的生化关联]
Fiziol Zh SSSR Im I M Sechenova. 1976 Feb;62(2):153-9.
4
[Cytochemical indices of intercentral interrelations of the motor and visual analyzers during light deprivation].[光剥夺期间运动和视觉分析器中枢间相互关系的细胞化学指标]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):997-1002.
5
[Biochemical characteristics of subcellular components of the visual system following light deprivation].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Mar-Apr;27(2):306-13.
6
[Changes in glutamate dehydrogenase activity in the neurons of the motor cortexof the cerebral hemispheres during light deprivation].[光剥夺期间大脑半球运动皮层神经元中谷氨酸脱氢酶活性的变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1978 Mar-Apr;28(2):402-7.
7
[RNA concentration in neuron-neuroglia systems of the retina and visual zones of the cerebral cortex during light deprivation and light stimulation].[光剥夺和光刺激期间视网膜及大脑皮质视觉区神经元-神经胶质系统中的RNA浓度]
Biull Eksp Biol Med. 1976;82(11):1332-4.
8
[The activity of several enzymes in visual cortex neurons following early interruption of visual function].
Zh Nevropatol Psikhiatr Im S S Korsakova. 1974;74(9):1345-9.
9
[Biochemical characteristics of cerebral cortex neurocyte development following early exclusion of photic afferentation].[早期排除光传入后大脑皮质神经细胞发育的生化特征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(7):961-6.
10
[Effect of light deprivation and light stimulation on the RNA content of neurons in the adult rat visual analyzer].[成年大鼠视觉分析器中光剥夺和光刺激对神经元RNA含量的影响]
Tsitologiia. 1975 Jan;17(1):73-7.

引用本文的文献

1
Glutamate dehydrogenase activity in motor cortex neurons during recovery of impaired visual function.视觉功能受损恢复过程中运动皮层神经元的谷氨酸脱氢酶活性
Neurosci Behav Physiol. 1981 Nov-Dec;11(6):570-4. doi: 10.1007/BF01186834.
2
Effect of early light deprivation on acetylcholinesterase activity in the visual cortex.
Neurosci Behav Physiol. 1983 Mar-Apr;13(2):122-5. doi: 10.1007/BF01190795.