Busniuk M M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976 Dec;76(12):1806-10.
With the aid of cytophotometry the author studied the cellular chemistry of neurons (according to the activity of glutamate dehydrogenase) in the III, IV and V layers of the visual cortex in rats during the period of rehabilitation of specific functions following long-term light deprivation. It was demonstrated that a 2-week stay of deprivated animals in conditions of usual light is accompanied by visible normalization of the glutamate dehydrogenase activity in the cortical neurons. However, a complete rehabilitation of the control level was not attained. The study demonstrated differences in the reactions of identical neurons in the IV and V layers to the rehabilitation of specific functions. It is being assumed that the rehabilitation of the visual function may be due to biochemical reconstructions in the monomodel and certain parts of the polymodal neurons in the visual cortex.
借助细胞光度测量法,作者研究了长期光照剥夺后特定功能恢复期间大鼠视觉皮层第III、IV和V层神经元的细胞化学(根据谷氨酸脱氢酶的活性)。结果表明,剥夺光照的动物在正常光照条件下饲养2周,其皮层神经元中谷氨酸脱氢酶活性明显恢复正常。然而,并未达到对照水平的完全恢复。研究表明,第IV和V层相同神经元对特定功能恢复的反应存在差异。据推测,视觉功能的恢复可能归因于视觉皮层单模式和多模式神经元某些部分的生化重建。