Spear N E
Act Nerv Super (Praha). 1976;18(4):302-11.
Although rats may show extensive forgetting if a long interval is interpolated between an aversive-conditioning episode and a retention test, this forgetting can be alleviated by a variety of reactivation treatment. This paper reports several experiments analyzing the consequences of one reactivation treatment - noncontingent presentation, between conditioning and testing, of the unconditioned stimulus - when applied to rats which differ in the age at which they are given their conditioning episode. After a long retention interval, both paradigms tested using this reactivation treatment are relatively ineffective for animals conditioned when 16--17 days of age, although both paradigms markedly alleviate forgetting when such immature animals are tested after relatively short retention intervals (a similar effect seems to occur with very old rats). Implications of this finding are tested and discussed.
虽然如果在厌恶条件反射事件和记忆保持测试之间插入较长的时间间隔，大鼠可能会表现出广泛的遗忘，但这种遗忘可以通过多种重新激活处理得到缓解。本文报告了几项实验，分析了一种重新激活处理——在条件反射和测试之间非条件刺激的非偶然性呈现——应用于在接受条件反射事件时年龄不同的大鼠时的后果。在较长的记忆保持间隔后，使用这种重新激活处理测试的两种范式对16 - 17天大时接受条件反射的动物相对无效，尽管当这些未成熟动物在相对较短的记忆保持间隔后进行测试时，两种范式都能显著减轻遗忘（非常年老的大鼠似乎也有类似的效果）。这一发现的含义得到了检验和讨论。
