Dunn E J, Kent T, Hines J, Cohn I
Ann Surg. 1976 Oct;184(4):500-6. doi: 10.1097/00000658-197610000-00013.
A 25-year experience with parotid tumors was reviewed. From a total of 250 neoplasms, 173 were histologically benign and 77 were malignant. Benign mixed tumors accounted for 59% of all lesions. Clinical parameters used to diagnose parotid neoplasms were found to be unreliable in determining whether a given tumor was benign or malignant. The mean age for malignant lesions was 10 years greater than for benign lesions. The phenomenon of malignant transformation of a benign tumor was considered in four patients. Complete surgical excision is the safest and preferred method for diagnosis. Preoperative needle or incisional biopsy are associated with a high degree of local recurrence. The appropriate management of any parotid tumor is predicated on special histological type. Local excision or enucleation no longer have a place in the surgical management of benign parotid tumors. Postoperative tumor recurrence and morbidity are directly related to awareness of surgical anatomy and pursuit of correct surgical techniques for adequate resection. The five-year recurrence rate for 102 benign mixed tumors was 6%. Recurrence in malignant tumors varied with specific histological types but was generally high. Five-year survival for all malignant parotid tumors was 48%.
回顾了25年的腮腺肿瘤治疗经验。在总共250例肿瘤中,173例组织学上为良性,77例为恶性。多形性腺瘤占所有病变的59%。发现用于诊断腮腺肿瘤的临床参数在确定某一特定肿瘤是良性还是恶性方面不可靠。恶性病变的平均年龄比良性病变大10岁。4例患者考虑了良性肿瘤恶变的现象。完整的手术切除是最安全且首选的诊断方法。术前针吸活检或切开活检与高度的局部复发相关。任何腮腺肿瘤的恰当处理取决于特殊的组织学类型。局部切除或剜除术在腮腺良性肿瘤的手术治疗中已不再适用。术后肿瘤复发和发病率与对手术解剖结构的了解以及采用正确的手术技术进行充分切除直接相关。102例多形性腺瘤的五年复发率为6%。恶性肿瘤的复发因具体组织学类型而异,但总体较高。所有腮腺恶性肿瘤的五年生存率为48%。