Nikolaev Iu M
Arkh Patol. 1976;38(7):38-44.
Morphological studies of the pancreas in patients who had died of peritonitis at various periods of its development were carried out. Moreover, an experiment was fulfiled on reproducing peritonitis on 41 dogs. In the pancreas in all sectional observations there was observed a picture of acute inflammatory process of a various degree of intensity (peritonitogenic pancreatitis) depending upon the form of peritonitis. It was established that in pathogenesis of acute peritonitogenic pancreatitis an important role was played by direct transfer of the inflammatory process to the tissue of the gland on the side of the abdominal cavity. At the same time, of great importance were also regurgitation of the intestinal content into the system of the excretory ducts of the gland and hemodynamic disorders. The morphological picture of the reproduced in the experiment on dogs acute peritonitogenic pancreatitis was similar to that in the section observations. Both sectional and experimental data confirm the duct-enzymatic theory, or the theory of "common canal", of the pathogenesis of pancreatitis in general of and peritonitogenic pancreatitis in particular.
对在腹膜炎发展不同阶段死亡的患者的胰腺进行了形态学研究。此外，还对41只狗进行了复制腹膜炎的实验。在所有切片观察中，胰腺呈现出不同强度的急性炎症过程（腹膜炎源性胰腺炎），这取决于腹膜炎的类型。已确定，在急性腹膜炎源性胰腺炎的发病机制中，炎症过程从腹腔一侧直接转移至腺体组织起着重要作用。与此同时，肠内容物反流至腺体排泄管道系统以及血液动力学紊乱也具有重要意义。在狗身上复制的急性腹膜炎源性胰腺炎的形态学表现与切片观察中的相似。切片和实验数据均证实了胰腺炎尤其是腹膜炎源性胰腺炎发病机制的导管 - 酶理论，即“共同通道”理论。
