Ramadan A, Nussenblatt R B
National Eye Institute, Laboratory of Immunology, National Institutes of Health, Bethesda, MD 20892-1858, USA.
Curr Opin Ophthalmol. 1996 Jun;7(3):39-45. doi: 10.1097/00055735-199606000-00007.
Sympathetic ophthalmia is probably the ocular disorder best known to practitioners outside of ophthalmology. It is characterized by a bilateral, nonnecrotizing granulomatous panuveitis that occurs after intentional or unintentional trauma to the exciting eye. So far, the identity of the inciting antigen has not been delineated with certainty. The sequelae from sympathetic ophthalmia have declined markedly in this century as a result of earlier diagnosis, use of corticosteroids, and better management of ocular injuries, in large part due to improved surgical techniques. Cases of sympathetic ophthalmia, however, still occur with their severe sight-threatening complications, which impose on ophthalmologists the importance of prompt diagnosis and aggressive treatment in order to achieve good visual outcome.
交感性眼炎可能是眼科以外的从业者最为熟知的眼部疾病。其特征为在激发眼受到有意或无意的外伤后,发生双侧、非坏死性肉芽肿性全葡萄膜炎。到目前为止,引发抗原的身份尚未明确界定。由于早期诊断、皮质类固醇的使用以及眼部损伤的更好管理,在很大程度上得益于手术技术的改进,本世纪交感性眼炎的后遗症已显著减少。然而,交感性眼炎病例仍会出现严重的视力威胁并发症,这使眼科医生认识到及时诊断和积极治疗对于获得良好视觉效果的重要性。