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[霍乱弧菌神经氨酸酶对劳舍尔小鼠白血病的抑制作用]

[Inhibiting effect of cholera vibrio neuraminidase in Rauscher mouse leukemia].

作者信息

Barinskiĭ I F, Korbinskiĭ G D

出版信息

Biull Eksp Biol Med. 1976;82(11):1357-9.

PMID:1016719
Abstract

A study was made of the inhibitory effect of neuraminidase of cholera vibrio in mouse Rauscher leukemia. It was shown that the processing of cells of the spleen of mice suffering from leukemia with neuraminidase (in a dose of 50 units/ml and more) significantly inhibited the capacity of these cells to induce leukemia in their injection to BALB/c mice. In the mentioned concentration neuraminidase injected repeatedly parenterally produced no therapeutic effect in Rauscher leukemia.

摘要

对霍乱弧菌神经氨酸酶对小鼠劳舍尔白血病的抑制作用进行了研究。结果表明,用神经氨酸酶(剂量为50单位/毫升及以上)处理患白血病小鼠的脾脏细胞,显著抑制了这些细胞在注射给BALB/c小鼠时诱发白血病的能力。在上述浓度下,经胃肠外反复注射神经氨酸酶对劳舍尔白血病没有治疗效果。

相似文献

1
[Inhibiting effect of cholera vibrio neuraminidase in Rauscher mouse leukemia].[霍乱弧菌神经氨酸酶对劳舍尔小鼠白血病的抑制作用]
Biull Eksp Biol Med. 1976;82(11):1357-9.
2
[Inhibitory effect of combined administration of neuraminidase and interferon in mice with Rauscher leukemia].[神经氨酸酶与干扰素联合给药对劳舍尔白血病小鼠的抑制作用]
Biull Eksp Biol Med. 1982 Jan;93(1):62-4.
3
[Evaluation of leukemogenic and immunogenic properties of leukemic cells modified by neuraminidase of non-cholera Vibrios on the model of Rauscher leukemia].[在劳舍尔白血病模型上评估非霍乱弧菌神经氨酸酶修饰的白血病细胞的致白血病性和免疫原性]
Eksp Onkol. 1985;7(2):56-60.
4
[Mechanism of the modifying effect of neuraminidase of the influenza virus on the development of Rauscher leukemia].
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5
[Reduction of the biological activity of Vibrio cholerae culture filtrates exposed to neuraminidase inhibitors].[暴露于神经氨酸酶抑制剂的霍乱弧菌培养滤液生物活性的降低]
Biull Eksp Biol Med. 1976;81(4):452-4.
6
[Use of the enzyme neuraminidase for immunotherapeutic treatment of chemically induced carcinogenesis].
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[Directed attacks on the specific activity of leukemia cells].[针对白血病细胞特定活性的定向攻击]
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8
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Loading of the reticuloendothelial system: effect on the induction, development and chemotherapy of Rauscher virus leukemia.网状内皮系统的负荷:对劳斯氏病毒白血病诱导、发展及化疗的影响
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