Hall R R, Wadehra V, Towler J M, Hindmarsh J R, Byrne P O
Br J Urol. 1976;48(7):603-8. doi: 10.1111/j.1464-410x.1976.tb06707.x.
High temperature bladder irrigation was employed in 4 men as an alternative to cystectomy because of their age and frailty. Hyperthermic irrigation of the bladder from 63 degree C for 70 minutes to 82 degree C for 25 minutes caused partial, but not total, necrosis of the bladder. Transitional cell carcinoma appears to be resistant in vivo, in some cases, to heating at temperatures that destroy adjacent normal structures. Hyperthermic irrigation of the bladder at these high temperatures may be hazardous. In view of these findings we cannot recommend high temperature bladder irrigation as an alternative to cystectomy even in poor risk patients.
由于年龄和身体虚弱，4名男性采用了高温膀胱灌注作为膀胱切除术的替代方法。膀胱高温灌注温度从63摄氏度持续70分钟到82摄氏度持续25分钟，导致膀胱部分而非全部坏死。在某些情况下，移行细胞癌在体内似乎对破坏相邻正常结构的温度加热具有抗性。在这些高温下进行膀胱高温灌注可能是危险的。鉴于这些发现，即使对于风险较高的患者，我们也不建议将高温膀胱灌注作为膀胱切除术的替代方法。
