Tengvall P, Lundström I
Linköping University, Department of Physics and Measurement Technology, Sweden.
Clin Mater. 1992;9(2):115-34. doi: 10.1016/0267-6605(92)90056-y.
Physico-chemical properties of titanium are discussed. Special attention is paid to those of amorphous TiO 2 that contact tissues in vivo. In aqueous environments TiO 2. (aq) has low ion-formation tendency and low reactivity with macromolecules. This is accompanied by low toxicity. Titanium does not facilitate reactive oxygen radical generation during inflammatory conditions as observed in in-vitro experiments. The outermost layers of the oxide are in the Ti(IV) oxidation state, although using electron spin resonance (ESR) techniques, formation of Ti(III) is observed at atmospheric conditions. The impact of similarities between water and TiO 2 is speculated upon, and the physico-chemical properties of titanium are tentatively linked to some in-vivo consequences.
讨论了钛的物理化学性质。特别关注了体内与组织接触的非晶态TiO₂的性质。在水性环境中，TiO₂(aq)具有低离子形成倾向且与大分子的反应性低。这伴随着低毒性。如体外实验所示，在炎症条件下钛不会促进活性氧自由基的产生。氧化物的最外层处于Ti(IV)氧化态，尽管使用电子自旋共振(ESR)技术，在大气条件下观察到Ti(III)的形成。推测了水和TiO₂之间相似性的影响，并初步将钛的物理化学性质与一些体内结果联系起来。
